Name | Euphorbia factor L1 |
Synonyms | euphoria factor L1 EUPATOROXIN,10-EPI Euphorbia factor L1 (E)-1,1,3,6-tetramethyl-4-oxo-7-(2-phenylacetoxy)-1,1a,4,4a,5,6,7,7a,8,10,11,11a-dodecahydrospiro[cyclopenta[a]cyclopropa[f][11]annulene-9,2'-oxiran]-4a,8-diyl diacetate Benzeneacetic acid, (1aR,2'S,4aR,6S,7S,7aR,8R,11aS)-4a,8-bis(acetyloxy)-1a,4a,5,6,7,7a,8,10,11,11a-decahydro-1,1,3,6-tetramethyl-4-oxospiro[9H-cyclopenta[a]cyclopropa[f]cycloundecene-9,2'-oxiran]-7-yl ester |
CAS | 76376-43-7 |
Molecular Formula | C32H40O8 |
Molar Mass | 552.66 |
Density | 1.23±0.1 g/cm3(Predicted) |
Boling Point | 633.1±55.0 °C(Predicted) |
Solubility | Soluble in chloroform. |
Appearance | White powder or crystal |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., is derived from the Euphorbia lathylris L. |
Biological activity | Euphorbia Factor L1 is a diterpenoid compound in Diospora, which can reduce Bcl-2,PI3K,AKT and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels, but have no effect on caspase-9 and caspase-3 protease. Euphorbia Factor L1 can induce autophagy (apoptosis) and has anti-cancer, anti-adipogenesis, anti-osteoclast generation and multi-drug resistance regulation effects. |
chemical properties | white crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from the Euphorbia lathylris L. |
use | Euphorbia factor L1 has anti-tumor effect. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: anti-tumor, anti-inflammatory |